3-Heptylidene-4,6-Dimethoxy-3H-Isobenzofuran-1-One Is Genotoxic, Increases the Frequency of Cell Death, and Potentiates the Effects of Cyclophosphamide and Cisplatin

3-heptylidene-4,6-dimethoxy-3H-isobenzofuran-1-one (Phthalide 1) is the precursor of three resorcinol lipids that have been described as potential chemotherapeutic agents and capable of potentiating the effects of cyclophosphamide. In this study, we evaluated the genotoxic potential, cell-killing po...

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Detalles Bibliográficos
Autores principales: das Neves, Silvia Cordeiro, de Araújo, Flavio Henrique, Correa, Willian Ayala, Martins, Allana Cristina Faustino, Coelho, Henrique Rodrigues Scherer, Vilela, Marcelo Luiz Brandão, do Nascimento, Valter Aragão, Kassuya, Candida Aparecida Leite, de Lima, Dênis Pires, Beatriz, Adilson, Oliveira, Rodrigo Juliano, Gomes, Roberto da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922015/
https://www.ncbi.nlm.nih.gov/pubmed/36770711
http://dx.doi.org/10.3390/molecules28031044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922015/
https://www.ncbi.nlm.nih.gov/pubmed/36770711
http://dx.doi.org/10.3390/molecules28031044

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