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Mitochondrial genome recovery by ATFS-1 is essential for development after starvation

Nutrient availability regulates the C. elegans life cycle as well as mitochondrial physiology. Food deprivation significantly reduces mitochondrial genome (mtDNA) numbers and leads to aging-related phenotypes. Here we show that the bZIP (basic leucine zipper) protein ATFS-1, a mediator of the mitoch...

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Detalles Bibliográficos
Autores principales: Naresh, Nandhitha Uma, Kim, Sookyung, Shpilka, Tomer, Yang, Qiyuan, Du, Yunguang, Haynes, Cole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922093/
https://www.ncbi.nlm.nih.gov/pubmed/36577367
http://dx.doi.org/10.1016/j.celrep.2022.111875