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Mitochondrial genome recovery by ATFS-1 is essential for development after starvation
Nutrient availability regulates the C. elegans life cycle as well as mitochondrial physiology. Food deprivation significantly reduces mitochondrial genome (mtDNA) numbers and leads to aging-related phenotypes. Here we show that the bZIP (basic leucine zipper) protein ATFS-1, a mediator of the mitoch...
Autores principales: | Naresh, Nandhitha Uma, Kim, Sookyung, Shpilka, Tomer, Yang, Qiyuan, Du, Yunguang, Haynes, Cole M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922093/ https://www.ncbi.nlm.nih.gov/pubmed/36577367 http://dx.doi.org/10.1016/j.celrep.2022.111875 |
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