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The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition

Both epithelial-to-mesenchymal (EMT) and endothelial-to-mesenchymal (EndMT) transitions have shown to contribute to the development and progression of kidney fibrosis. It has been reported that apelin, a regulatory peptide, alleviates EMT by inhibiting the transforming growth factor β (TGFβ) pathway...

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Detalles Bibliográficos
Autores principales: Gao, Rongfen, Wu, Yumin, Yang, Qian, Chen, Liangdong, Chen, Jiwei, Wang, Boyong, Liu, Zeming, Jin, Juan, Li, Jinpeng, Wu, Gaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922196/
https://www.ncbi.nlm.nih.gov/pubmed/36785790
http://dx.doi.org/10.1155/2023/5012474