DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombomodulin in Fuchs endothelial corneal dystrophy

Late-onset Fuchs endothelial corneal dystrophy (FECD) is a disease affecting the corneal endothelium (CE), associated with a cytosine-thymine-guanine repeat expansion at the CTG18.1 locus in the transcription factor 4 (TCF4) gene. It is unknown whether CTG18.1 expansions affect global methylation in...

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Detalles Bibliográficos
Autores principales: Westin, Ida Maria, Landfors, Mattias, Giannopoulos, Antonios, Viberg, Andreas, Osterman, Pia, Byström, Berit, Degerman, Sofie, Golovleva, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922242/
https://www.ncbi.nlm.nih.gov/pubmed/36773096
http://dx.doi.org/10.1007/s00018-023-04714-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922242/
https://www.ncbi.nlm.nih.gov/pubmed/36773096
http://dx.doi.org/10.1007/s00018-023-04714-x

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