NMDARs antagonist MK801 suppresses LPS-induced apoptosis and mitochondrial dysfunction by regulating subunits of NMDARs via the CaM/CaMKII/ERK pathway

Lipopolysaccharide (LPS) displays a robust immunostimulatory ability upon Toll-like receptor 4 (TLR4) recognition. N-methyl-D-aspartate receptors (NMDARs) are highly compartmentalized in most cells and implicated in various inflammatory disorders. However, the relationship between TLR4 and NMDARs ha...

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Detalles Bibliográficos
Autores principales: Han, Wei-Min, Hao, Xiao-Bin, Hong, Yi-Xiang, Zhao, Shan-Shan, Chen, Xu-Chang, Wang, Ruiying, Wang, Yan, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922289/
https://www.ncbi.nlm.nih.gov/pubmed/36774369
http://dx.doi.org/10.1038/s41420-023-01362-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922289/
https://www.ncbi.nlm.nih.gov/pubmed/36774369
http://dx.doi.org/10.1038/s41420-023-01362-9

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