Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex

The S. pombe orthologue of the human PAXT connection, Mtl1-Red1 Core (MTREC), is an eleven-subunit complex that targets cryptic unstable transcripts (CUTs) to the nuclear RNA exosome for degradation. It encompasses the canonical poly(A) polymerase Pla1, responsible for polyadenylation of nascent RNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Soni, Komal, Sivadas, Anusree, Horvath, Attila, Dobrev, Nikolay, Hayashi, Rippei, Kiss, Leo, Simon, Bernd, Wild, Klemens, Sinning, Irmgard, Fischer, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922296/
https://www.ncbi.nlm.nih.gov/pubmed/36774373
http://dx.doi.org/10.1038/s41467-023-36402-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922296/
https://www.ncbi.nlm.nih.gov/pubmed/36774373
http://dx.doi.org/10.1038/s41467-023-36402-6

Ejemplares similares