Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

Intravascular hemolysis occurs in diverse pathological conditions. Extracellular hemoglobin and heme have strong pro-oxidative and pro-inflammatory potentials that can contribute to the pathology of hemolytic diseases. However, many of the effects of extracellular hemoglobin and heme in hemolytic di...

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Detalles Bibliográficos
Autores principales: Planchais, Cyril, Noe, Remi, Gilbert, Marie, Lecerf, Maxime, Kaveri, Srini V., Lacroix-Desmazes, Sébastien, Roumenina, Lubka T., Dimitrov, Jordan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922299/
https://www.ncbi.nlm.nih.gov/pubmed/36774392
http://dx.doi.org/10.1038/s42003-023-04535-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922299/
https://www.ncbi.nlm.nih.gov/pubmed/36774392
http://dx.doi.org/10.1038/s42003-023-04535-5

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