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Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme
Intravascular hemolysis occurs in diverse pathological conditions. Extracellular hemoglobin and heme have strong pro-oxidative and pro-inflammatory potentials that can contribute to the pathology of hemolytic diseases. However, many of the effects of extracellular hemoglobin and heme in hemolytic di...
Autores principales: | Planchais, Cyril, Noe, Remi, Gilbert, Marie, Lecerf, Maxime, Kaveri, Srini V., Lacroix-Desmazes, Sébastien, Roumenina, Lubka T., Dimitrov, Jordan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922299/ https://www.ncbi.nlm.nih.gov/pubmed/36774392 http://dx.doi.org/10.1038/s42003-023-04535-5 |
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