A cooperative nano-CRISPR scaffold potentiates immunotherapy via activation of tumour-intrinsic pyroptosis

Efficient cancer immunotherapy depends on selective targeting of high bioactivity therapeutic agents to the tumours. However, delivering exogenous medication might prove difficult in clinical practice. Here we report a cooperative Nano-CRISPR scaffold (Nano-CD) that utilizes a specific sgRNA, select...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Liu, Chao, Li, Yingjie, Huang, Dongxue, Wu, Xinyue, Kou, Xiaorong, Wang, Xiye, Wu, Qinjie, Gong, Changyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922300/
https://www.ncbi.nlm.nih.gov/pubmed/36774382
http://dx.doi.org/10.1038/s41467-023-36550-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922300/
https://www.ncbi.nlm.nih.gov/pubmed/36774382
http://dx.doi.org/10.1038/s41467-023-36550-9

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