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Genomic and microenvironmental heterogeneity shaping epithelial-to-mesenchymal trajectories in cancer

The epithelial to mesenchymal transition (EMT) is a key cellular process underlying cancer progression, with multiple intermediate states whose molecular hallmarks remain poorly characterised. To fill this gap, we present a method to robustly evaluate EMT transformation in individual tumours based o...

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Detalles Bibliográficos
Autores principales: Malagoli Tagliazucchi, Guidantonio, Wiecek, Anna J., Withnell, Eloise, Secrier, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922305/
https://www.ncbi.nlm.nih.gov/pubmed/36774358
http://dx.doi.org/10.1038/s41467-023-36439-7