Coupling of autophagy and the mitochondrial intrinsic apoptosis pathway modulates proteostasis and ageing in Caenorhabditis elegans

Mitochondria preserve metabolic homeostasis and integrate stress signals, to trigger cytoprotective, or cell death pathways. Mitochondrial homeostasis and function decline with age. The mechanisms underlying the deterioration of mitochondrial homeostasis during ageing, or in age-associated pathologi...

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Detalles Bibliográficos
Autores principales: Ploumi, Christina, Kyriakakis, Emmanouil, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922313/
https://www.ncbi.nlm.nih.gov/pubmed/36774344
http://dx.doi.org/10.1038/s41419-023-05638-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922313/
https://www.ncbi.nlm.nih.gov/pubmed/36774344
http://dx.doi.org/10.1038/s41419-023-05638-x

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