Cargando…

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway

Major pathological features of Parkinson’s disease (PD) include increase in oxidative stress leading to the aggregation of α-synuclein, mitochondrial dysfunction and apoptosis of dopaminergic neurons. In addition, downregulation of the expression of neurotrophic factors like-Brain Derived Neurotroph...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Richa, Zahra, Walia, Singh, Saumitra Sen, Birla, Hareram, Rathore, Aaina Singh, Keshri, Priyanka Kumari, Dilnashin, Hagera, Singh, Shekhar, Singh, Surya Pratap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922328/
https://www.ncbi.nlm.nih.gov/pubmed/36774383
http://dx.doi.org/10.1038/s41598-023-29287-4