Cargando…

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

BACKGROUND: Selectively targeting leukemia stem cells (LSCs) is a promising approach in treating acute myeloid leukemia (AML), for which identification of such therapeutic targets is critical. Increasing lines of evidence indicate that FBXO22 plays a critical role in solid tumor development and ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Xiao-Na, Wei, Yu-Sheng, Yang, Qian, Liu, Hao-Ran, Zhi, Zhe, Zhu, Di, Xia, Li, Hong, Deng-Li, Yu, Yun, Chen, Guo-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922468/
https://www.ncbi.nlm.nih.gov/pubmed/36774506
http://dx.doi.org/10.1186/s13045-023-01400-0