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Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice

Chemotherapy-induced peripheral neuropathy (CIPN) is a primary dose-limiting side effect caused by antineoplastic agents, such as paclitaxel. A primary symptom of this neuropathy is pain. Currently, there are no effective treatments for CIPN, which can lead to long-term morbidity in cancer patients...

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Detalles Bibliográficos
Autores principales: Sankaranarayanan, Ishwarya, Tavares-Ferreira, Diana, Mwirigi, Juliet M., Mejia, Galo L., Burton, Michael D., Price, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922469/
https://www.ncbi.nlm.nih.gov/pubmed/36774519
http://dx.doi.org/10.1186/s12974-023-02719-8