Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning

Pancreatic islet transplantation in diabetes is limited by requirements for systemic immunosuppression to prevent rejection. Chang et al. report a non-toxic bone marrow conditioning regimen targeting c-Kit that permits stable mixed hematopoietic chimerism across major histocompatibility complex barr...

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Detalles Bibliográficos
Autores principales: Chang, Charles A., Bhagchandani, Preksha, Poyser, Jessica, Velasco, Brenda J., Zhao, Weichen, Kwon, Hye-Sook, Meyer, Everett, Shizuru, Judith A., Kim, Seung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922474/
https://www.ncbi.nlm.nih.gov/pubmed/36351397
http://dx.doi.org/10.1016/j.celrep.2022.111615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922474/
https://www.ncbi.nlm.nih.gov/pubmed/36351397
http://dx.doi.org/10.1016/j.celrep.2022.111615

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