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Allergen-specific immunotherapy with Alutard SQ improves allergic inflammation in house-dust mites-induced allergic asthma rats through inactivation of the HMGB1/TLR4/NF-κB pathway

BACKGROUND: Allergen-specific immunotherapy (AIT) is the only available safe, effective, and long-term treatment for allergic airway diseases, including allergic asthma. However, the potential molecular mechanism of AIT in ameliorating airway inflammation remains unknown. METHODS: Rats were sensitiz...

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Detalles Bibliográficos
Autores principales: Zhai, Yingying, Zheng, Peiyan, Sun, Baoqing, Li, Jing, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922602/
https://www.ncbi.nlm.nih.gov/pubmed/36794148
http://dx.doi.org/10.21037/jtd-22-715