Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids

BACKGROUND: The epithelium in the colonic mucosa is implicated in the pathophysiology of various diseases, including inflammatory bowel diseases and colorectal cancer. Intestinal epithelial organoids from the colon (colonoids) can be used for disease modeling and personalized drug screening. Colonoi...

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Detalles Bibliográficos
Autores principales: Walaas, Gunnar Andreas, Gopalakrishnan, Shreya, Bakke, Ingunn, Skovdahl, Helene Kolstad, Flatberg, Arnar, Østvik, Ann Elisabet, Sandvik, Arne Kristian, Bruland, Torunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922616/
https://www.ncbi.nlm.nih.gov/pubmed/36793710
http://dx.doi.org/10.3389/fimmu.2023.1095812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922616/
https://www.ncbi.nlm.nih.gov/pubmed/36793710
http://dx.doi.org/10.3389/fimmu.2023.1095812

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