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Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle

OBJECTIVE: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis. Other mechanisms, including metabolism of skeletal muscle, m...

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Detalles Bibliográficos
Autores principales: Janovska, Petra, Zouhar, Petr, Bardova, Kristina, Otahal, Jakub, Vrbacky, Marek, Mracek, Tomas, Adamcova, Katerina, Lenkova, Lucie, Funda, Jiri, Cajka, Tomas, Drahota, Zdenek, Stanic, Sara, Rustan, Arild C., Horakova, Olga, Houstek, Josef, Rossmeisl, Martin, Kopecky, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922683/
https://www.ncbi.nlm.nih.gov/pubmed/36720306
http://dx.doi.org/10.1016/j.molmet.2023.101683