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Therapeutic targeting of mineralocorticoid receptors in pulmonary hypertension: Insights from basic research

Pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling and associated with adverse outcomes. In patients with PH, plasma aldosterone levels are elevated, suggesting that aldosterone and its receptor, the mineralocorticoid receptor (MR), play an important role in the pathophysi...

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Detalles Bibliográficos
Autores principales: Mamazhakypov, Argen, Lother, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922727/
https://www.ncbi.nlm.nih.gov/pubmed/36793473
http://dx.doi.org/10.3389/fcvm.2023.1118516