Magel2 truncation alters select behavioral and physiological outcomes in a rat model of Schaaf-Yang syndrome

Previous studies in mice have utilized Magel2 gene deletion models to examine the consequences of its absence. We report the generation, molecular validation and phenotypic characterization of a novel rat model with a truncating Magel2 mutation modeling variants associated with Schaaf-Yang syndrome-...

Descripción completa

Detalles Bibliográficos
Autores principales: Reznik, Derek L., Yang, Mingxiao V., Albelda de la Haza, Pedro, Jain, Antrix, Spanjaard, Melanie, Theiss, Susanne, Schaaf, Christian P., Malovannaya, Anna, Strong, Theresa V., Veeraragavan, Surabi, Samaco, Rodney C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922728/
https://www.ncbi.nlm.nih.gov/pubmed/36637363
http://dx.doi.org/10.1242/dmm.049829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922728/
https://www.ncbi.nlm.nih.gov/pubmed/36637363
http://dx.doi.org/10.1242/dmm.049829

Ejemplares similares