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Magel2 truncation alters select behavioral and physiological outcomes in a rat model of Schaaf-Yang syndrome

Previous studies in mice have utilized Magel2 gene deletion models to examine the consequences of its absence. We report the generation, molecular validation and phenotypic characterization of a novel rat model with a truncating Magel2 mutation modeling variants associated with Schaaf-Yang syndrome-...

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Detalles Bibliográficos
Autores principales:	Reznik, Derek L., Yang, Mingxiao V., Albelda de la Haza, Pedro, Jain, Antrix, Spanjaard, Melanie, Theiss, Susanne, Schaaf, Christian P., Malovannaya, Anna, Strong, Theresa V., Veeraragavan, Surabi, Samaco, Rodney C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922728/ https://www.ncbi.nlm.nih.gov/pubmed/36637363 http://dx.doi.org/10.1242/dmm.049829

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