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The store-operated Ca(2+) channel Orai1α is required for agonist-evoked NF-κB activation by a mechanism dependent on PKCβ2

Store-operated Ca(2+) entry is a ubiquitous mechanism for Ca(2+) influx in mammalian cells that regulates a variety of physiological processes. The identification of two forms of Orai1, the predominant store-operated channel, Orai1α and Orai1β, raises the question whether they differentially regulat...

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Detalles Bibliográficos
Autores principales: Nieto-Felipe, Joel, Sanchez-Collado, Jose, Jardin, Isaac, Salido, Gines M., Lopez, Jose J., Rosado, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922819/
https://www.ncbi.nlm.nih.gov/pubmed/36623731
http://dx.doi.org/10.1016/j.jbc.2023.102882