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The penultimate step of proteasomal ATPase assembly is mediated by a switch dependent on the chaperone Nas2
The proteasome holoenzyme is a complex molecular machine that degrades most proteins. In the proteasome holoenzyme, six distinct ATPase subunits (Rpt1 through Rpt6) enable protein degradation by injecting protein substrates into it. Individual Rpt subunits assemble into a heterohexameric “Rpt ring”...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922823/ https://www.ncbi.nlm.nih.gov/pubmed/36621624 http://dx.doi.org/10.1016/j.jbc.2023.102870 |