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Reprogramming of adult human dermal fibroblasts to induced dorsal forebrain precursor cells maintains aging signatures
Introduction: With the increase in aging populations around the world, the development of in vitro human cell models to study neurodegenerative disease is crucial. A major limitation in using induced pluripotent stem cell (hiPSC) technology to model diseases of aging is that reprogramming fibroblast...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922835/ https://www.ncbi.nlm.nih.gov/pubmed/36794263 http://dx.doi.org/10.3389/fncel.2023.1003188 |