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Reprogramming of adult human dermal fibroblasts to induced dorsal forebrain precursor cells maintains aging signatures

Introduction: With the increase in aging populations around the world, the development of in vitro human cell models to study neurodegenerative disease is crucial. A major limitation in using induced pluripotent stem cell (hiPSC) technology to model diseases of aging is that reprogramming fibroblast...

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Detalles Bibliográficos
Autores principales:	McCaughey-Chapman, Amy, Tarczyluk-Wells, Marta, Combrinck, Catharina, Edwards, Nicole, Jones, Kathryn, Connor, Bronwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922835/ https://www.ncbi.nlm.nih.gov/pubmed/36794263 http://dx.doi.org/10.3389/fncel.2023.1003188

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