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Endothelial cell TRPA1 activity exacerbates cerebral hemorrhage during severe hypertension

Introduction: Hypoxia-induced dilation of cerebral arteries orchestrated by Ca(2+)-permeable transient receptor potential ankyrin 1 (TRPA1) cation channels on endothelial cells is neuroprotective during ischemic stroke, but it is unknown if the channel has a similar impact during hemorrhagic stroke....

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Detalles Bibliográficos
Autores principales: Sullivan, Michelle N., Thakore, Pratish, Krishnan, Vivek, Alphonsa, Sushma, Li, Wencheng, Feng Earley, Yumei, Earley, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922848/
https://www.ncbi.nlm.nih.gov/pubmed/36793787
http://dx.doi.org/10.3389/fmolb.2023.1129435