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A dynamical stochastic model of yeast translation across the cell cycle

Translation is a central step in gene expression, however its quantitative and time-resolved regulation is poorly understood. We developed a discrete, stochastic model for protein translation in S. cerevisiae in a whole-transcriptome, single-cell context. A “base case” scenario representing an avera...

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Detalles Bibliográficos
Autores principales: Seeger, Martin, Flöttmann, Max, Klipp, Edda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922973/
https://www.ncbi.nlm.nih.gov/pubmed/36793957
http://dx.doi.org/10.1016/j.heliyon.2023.e13101