SRA inhibition improves antitumor potency of antigen-targeted chaperone vaccine

We have previously demonstrated that scavenger receptor A (SRA) acts as an immunosuppressive regulator of dendritic cell (DC) function in activating antitumor T cells. Here we investigate the potential of inhibiting SRA activity to enhance DC-targeted chaperone vaccines including one that was recent...

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Detalles Bibliográficos
Autores principales: Qian, Jie, Yu, Xiaofei, Liu, Zheng, Cai, Jinyang, Manjili, Masoud H., Yang, Hu, Guo, Chunqing, Wang, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923017/
https://www.ncbi.nlm.nih.gov/pubmed/36793731
http://dx.doi.org/10.3389/fimmu.2023.1118781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923017/
https://www.ncbi.nlm.nih.gov/pubmed/36793731
http://dx.doi.org/10.3389/fimmu.2023.1118781

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