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Development and validation of an advanced ex vivo brain slice invasion assay to model glioblastoma cell invasion into the complex brain microenvironment

Organotypic cultures of murine brain slices are well-established tools in neuroscience research, including electrophysiology studies, modeling neurodegeneration, and cancer research. Here, we present an optimized ex vivo brain slice invasion assay that models glioblastoma multiforme (GBM) cell invas...

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Detalles Bibliográficos
Autores principales: Decotret, Lisa R., Shi, Rocky, Thomas, Kiersten N., Hsu, Manchi, Pallen, Catherine J., Bennewith, Kevin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923402/
https://www.ncbi.nlm.nih.gov/pubmed/36793608
http://dx.doi.org/10.3389/fonc.2023.976945