SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck

[Image: see text] A deficiency of the functional α7 nicotinic acetylcholine receptor (α7nAChR) impairs neuronal and immune systems. The SARS-CoV-2 spike protein (S12) facilitates virus cell entry during COVID-19 infection and can also independently disrupt cellular functions. Here, we found that S12...

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Detalles Bibliográficos
Autores principales: Tillman, Tommy S., Chen, Qiang, Bondarenko, Vasyl, Coleman, Jonathan A., Xu, Yan, Tang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923440/
https://www.ncbi.nlm.nih.gov/pubmed/36745901
http://dx.doi.org/10.1021/acschemneuro.2c00610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923440/
https://www.ncbi.nlm.nih.gov/pubmed/36745901
http://dx.doi.org/10.1021/acschemneuro.2c00610

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