Exploring the neuroprotective effects of montelukast on brain inflammation and metabolism in a rat model of quinolinic acid-induced striatal neurotoxicity

BACKGROUND: One intrastriatal administration of quinolinic acid (QA) in rats induces a lesion with features resembling those observed in Huntington’s disease. Our aim is to evaluate the effects of the cysteinyl leukotriene receptor antagonist montelukast (MLK), which exhibited neuroprotection in dif...

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Detalles Bibliográficos
Autores principales: Tassan Mazzocco, Margherita, Murtaj, Valentina, Martins, Daniel, Schellino, Roberta, Coliva, Angela, Toninelli, Elisa, Vercelli, Alessandro, Turkheimer, Federico, Belloli, Sara, Moresco, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923670/
https://www.ncbi.nlm.nih.gov/pubmed/36782185
http://dx.doi.org/10.1186/s12974-023-02714-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923670/
https://www.ncbi.nlm.nih.gov/pubmed/36782185
http://dx.doi.org/10.1186/s12974-023-02714-z

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