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Biotransformation of Bisphenol by Human Cytochrome P450 2C9 Enzymes: A Density Functional Theory Study

[Image: see text] Bisphenol A (BPA, 2,2-bis-(4-hydroxyphenyl)propane) is used as a precursor in the synthesis of polycarbonate and epoxy plastics; however, its availability in the environment is causing toxicity as an endocrine-disrupting chemical. Metabolism of BPA and their analogues (substitutes)...

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Detalles Bibliográficos
Autores principales: Hermano Sampaio Dias, Artur, Yadav, Rolly, Mokkawes, Thirakorn, Kumar, Asheesh, Skaf, Munir S., Sastri, Chivukula V., Kumar, Devesh, de Visser, Sam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923688/
https://www.ncbi.nlm.nih.gov/pubmed/36651185
http://dx.doi.org/10.1021/acs.inorgchem.2c03984