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Efficacy and safety of anti-interleukin-1 therapeutics in the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

OBJECTIVE: We aimed to evaluate the efficacy and safety of anti-interleukin-1 therapeutics, including IL-1 antibodies, interleukin-1 receptor antagonists (IL-1 Ras) and IL-1 inhibitors, for knee osteoarthritis (KOA) treatment. METHODS: Databases (Medline, Embase, Web of Science and CENTRAL) and Clin...

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Detalles Bibliográficos
Autores principales: Yu, Lizhi, Luo, Raoshan, Qin, Gang, Zhang, Qinyan, Liang, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923921/
https://www.ncbi.nlm.nih.gov/pubmed/36782214
http://dx.doi.org/10.1186/s13018-023-03590-2