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An engineered miRNA PS-OMe miR130 inhibits acute lung injury by targeting eCIRP in sepsis

BACKGROUND: Sepsis is caused by the dysregulated immune response due to an initial infection and results in significant morbidity and mortality in humans. Extracellular cold inducible RNA binding protein (eCIRP) is a novel mediator identified in sepsis. We have previously discovered that microRNA 13...

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Detalles Bibliográficos
Autores principales: Borjas, Timothy, Jacob, Asha, Kobritz, Molly, Ma, Gaifeng, Tan, Chuyi, Patel, Vihas, Coppa, Gene F., Aziz, Monowar, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923923/
https://www.ncbi.nlm.nih.gov/pubmed/36782115
http://dx.doi.org/10.1186/s10020-023-00607-8