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An engineered miRNA PS-OMe miR130 inhibits acute lung injury by targeting eCIRP in sepsis
BACKGROUND: Sepsis is caused by the dysregulated immune response due to an initial infection and results in significant morbidity and mortality in humans. Extracellular cold inducible RNA binding protein (eCIRP) is a novel mediator identified in sepsis. We have previously discovered that microRNA 13...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923923/ https://www.ncbi.nlm.nih.gov/pubmed/36782115 http://dx.doi.org/10.1186/s10020-023-00607-8 |