Cargando…

Structure, signal transduction, activation, and inhibition of integrin αIIbβ3

Integrins are heterodimeric receptors comprising α and β subunits. They are expressed on the cell surface and play key roles in cell adhesion, migration, and growth. Several types of integrins are expressed on the platelets, including αvβ3, αIIbβ3, α2β1, α5β1, and α6β1. Among these, physically αIIbβ...

Descripción completa

Detalles Bibliográficos
Autores principales: Xin, Honglei, Huang, Jiansong, Song, Zhiqun, Mao, Jianhua, Xi, Xiaodong, Shi, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923933/
https://www.ncbi.nlm.nih.gov/pubmed/36782235
http://dx.doi.org/10.1186/s12959-023-00463-w