Cargando…
Structure, signal transduction, activation, and inhibition of integrin αIIbβ3
Integrins are heterodimeric receptors comprising α and β subunits. They are expressed on the cell surface and play key roles in cell adhesion, migration, and growth. Several types of integrins are expressed on the platelets, including αvβ3, αIIbβ3, α2β1, α5β1, and α6β1. Among these, physically αIIbβ...
Autores principales: | Xin, Honglei, Huang, Jiansong, Song, Zhiqun, Mao, Jianhua, Xi, Xiaodong, Shi, Xiaofeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923933/ https://www.ncbi.nlm.nih.gov/pubmed/36782235 http://dx.doi.org/10.1186/s12959-023-00463-w |
Ejemplares similares
-
Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting
por: Huang, Jiansong, et al.
Publicado: (2019) -
Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis
por: Xu, Xiaohong Ruby, et al.
Publicado: (2018) -
New insights into regulation of αIIbβ3 integrin signaling by filamin A
por: Lamrani, Lamia, et al.
Publicado: (2022) -
Skelemin in Integrin α(IIb)β(3) Mediated Cell Spreading
por: Li, Xinlei, et al.
Publicado: (2012) -
Extract of Seaweed Codium fragile Inhibits Integrin αIIbβ3-Induced Outside-in Signaling and Arterial Thrombosis
por: Kim, Tae In, et al.
Publicado: (2021)