AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T(H)1 response with a diverse TCR repertoire

AZD1222 (ChAdOx1 nCoV-19), a replication-deficient simian adenovirus–vectored vaccine, has demonstrated safety, efficacy, and immunogenicity against coronavirus disease 2019 in clinical trials and real-world studies. We characterized CD4(+) and CD8(+) T cell responses induced by AZD1222 vaccination...

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Detalles Bibliográficos
Autores principales: Swanson, Phillip A., Padilla, Marcelino, Hoyland, Wesley, McGlinchey, Kelly, Fields, Paul A., Bibi, Sagida, Faust, Saul N., McDermott, Adrian B., Lambe, Teresa, Pollard, Andrew J., Durham, Nicholas M., Kelly, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924073/
https://www.ncbi.nlm.nih.gov/pubmed/34591596
http://dx.doi.org/10.1126/scitranslmed.abj7211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924073/
https://www.ncbi.nlm.nih.gov/pubmed/34591596
http://dx.doi.org/10.1126/scitranslmed.abj7211

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