Adjustment for baseline characteristics in randomized trials using logistic regression: sample-based model versus true model

BACKGROUND: Adjustment for baseline prognostic factors in randomized clinical trials is usually performed by means of sample-based regression models. Sample-based models may be incorrect due to overfitting. To assess whether overfitting is a problem in practice, we used simulated data to examine the...

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Detalles Bibliográficos
Autores principales: Perneger, Thomas, Combescure, Christophe, Poncet, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924183/
https://www.ncbi.nlm.nih.gov/pubmed/36782238
http://dx.doi.org/10.1186/s13063-022-07053-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924183/
https://www.ncbi.nlm.nih.gov/pubmed/36782238
http://dx.doi.org/10.1186/s13063-022-07053-7

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