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Adjustment for baseline characteristics in randomized trials using logistic regression: sample-based model versus true model
BACKGROUND: Adjustment for baseline prognostic factors in randomized clinical trials is usually performed by means of sample-based regression models. Sample-based models may be incorrect due to overfitting. To assess whether overfitting is a problem in practice, we used simulated data to examine the...
Autores principales: | Perneger, Thomas, Combescure, Christophe, Poncet, Antoine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924183/ https://www.ncbi.nlm.nih.gov/pubmed/36782238 http://dx.doi.org/10.1186/s13063-022-07053-7 |
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