Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia

To better understand clonal and transcriptional adaptations after relapse in patients with acute myeloid leukemia (AML), we collected presentation and relapse samples from six normal karyotype AML cases. We performed enhanced whole-genome sequencing to characterize clonal evolution, and deep-coverag...

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Detalles Bibliográficos
Autores principales: Petti, Allegra A., Khan, Saad M., Xu, Ziheng, Helton, Nichole, Fronick, Catrina C., Fulton, Robert, Ramakrishnan, Sai M., Nonavinkere Srivatsan, Sridhar, Heath, Sharon E., Westervelt, Peter, Payton, Jacqueline E., Walter, Matthew J., Link, Daniel C., DiPersio, John, Miller, Christopher, Ley, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924296/
https://www.ncbi.nlm.nih.gov/pubmed/35019859
http://dx.doi.org/10.1158/2643-3230.BCD-21-0050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924296/
https://www.ncbi.nlm.nih.gov/pubmed/35019859
http://dx.doi.org/10.1158/2643-3230.BCD-21-0050

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