TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy

Chemotherapy-induced peripheral neuropathy is a frequent, disabling side effect of anticancer drugs. Oxaliplatin, a platinum compound used in the treatment of advanced colorectal cancer, often leads to a form of chemotherapy-induced peripheral neuropathy characterized by mechanical and cold hypersen...

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Detalles Bibliográficos
Autores principales: Marcotti, Aida, Fernández-Trillo, Jorge, González, Alejandro, Vizcaíno-Escoto, Marta, Ros-Arlanzón, Pablo, Romero, Luz, Vela, José Miguel, Gomis, Ana, Viana, Félix, de la Peña, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924907/
https://www.ncbi.nlm.nih.gov/pubmed/35871491
http://dx.doi.org/10.1093/brain/awac273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924907/
https://www.ncbi.nlm.nih.gov/pubmed/35871491
http://dx.doi.org/10.1093/brain/awac273

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