Cargando…
TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy
Chemotherapy-induced peripheral neuropathy is a frequent, disabling side effect of anticancer drugs. Oxaliplatin, a platinum compound used in the treatment of advanced colorectal cancer, often leads to a form of chemotherapy-induced peripheral neuropathy characterized by mechanical and cold hypersen...
Autores principales: | Marcotti, Aida, Fernández-Trillo, Jorge, González, Alejandro, Vizcaíno-Escoto, Marta, Ros-Arlanzón, Pablo, Romero, Luz, Vela, José Miguel, Gomis, Ana, Viana, Félix, de la Peña, Elvira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924907/ https://www.ncbi.nlm.nih.gov/pubmed/35871491 http://dx.doi.org/10.1093/brain/awac273 |
Ejemplares similares
-
Oxaliplatin-Induced Peripheral Neuropathy via TRPA1 Stimulation in Mice Dorsal Root Ganglion Is Correlated with Aluminum Accumulation
por: Park, Jin-Hee, et al.
Publicado: (2015) -
A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain
por: Nativi, Cristina, et al.
Publicado: (2013) -
TRPA1 channel mediates organophosphate-induced delayed neuropathy
por: Ding, Qiang, et al.
Publicado: (2017) -
Role of PAR2 in regulating oxaliplatin-induced neuropathic pain via TRPA1
por: Tian, Liujun, et al.
Publicado: (2015) -
Management of oxaliplatin-induced peripheral neuropathy
por: Saif, M Wasif, et al.
Publicado: (2005)