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Platelet response to influenza vaccination reflects effects of aging

Platelets are uniquely positioned as mediators of not only hemostasis but also innate immunity. However, how age and geriatric conditions such as frailty influence platelet function during an immune response remains unclear. We assessed the platelet transcriptome at baseline and following influenza...

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Detalles Bibliográficos
Autores principales: Konstorum, Anna, Mohanty, Subhasis, Zhao, Yujiao, Melillo, Anthony, Vander Wyk, Brent, Nelson, Allison, Tsang, Sui, Blevins, Tamara P., Belshe, Robert B., Chawla, Daniel G., Rondina, Matthew T., Gill, Thomas M., Montgomery, Ruth R., Allore, Heather G., Kleinstein, Steven H., Shaw, Albert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924941/
https://www.ncbi.nlm.nih.gov/pubmed/36656789
http://dx.doi.org/10.1111/acel.13749