STAT3 promotes a youthful epigenetic state in articular chondrocytes

Epigenetic mechanisms guiding articular cartilage regeneration and age‐related disease such as osteoarthritis (OA) are poorly understood. STAT3 is a critical age‐patterned transcription factor highly active in fetal and OA chondrocytes, but the context‐specific role of STAT3 in regulating the epigen...

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Detalles Bibliográficos
Autores principales: Sarkar, Arijita, Liu, Nancy Q., Magallanes, Jenny, Tassey, Jade, Lee, Siyoung, Shkhyan, Ruzanna, Lee, Youngjoo, Lu, Jinxiu, Ouyang, Yuxin, Tang, Hanhan, Bian, Fangzhou, Tao, Litao, Segil, Neil, Ernst, Jason, Lyons, Karen, Horvath, Steve, Evseenko, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924946/
https://www.ncbi.nlm.nih.gov/pubmed/36638270
http://dx.doi.org/10.1111/acel.13773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924946/
https://www.ncbi.nlm.nih.gov/pubmed/36638270
http://dx.doi.org/10.1111/acel.13773

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