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STAT3 promotes a youthful epigenetic state in articular chondrocytes
Epigenetic mechanisms guiding articular cartilage regeneration and age‐related disease such as osteoarthritis (OA) are poorly understood. STAT3 is a critical age‐patterned transcription factor highly active in fetal and OA chondrocytes, but the context‐specific role of STAT3 in regulating the epigen...
Autores principales: | Sarkar, Arijita, Liu, Nancy Q., Magallanes, Jenny, Tassey, Jade, Lee, Siyoung, Shkhyan, Ruzanna, Lee, Youngjoo, Lu, Jinxiu, Ouyang, Yuxin, Tang, Hanhan, Bian, Fangzhou, Tao, Litao, Segil, Neil, Ernst, Jason, Lyons, Karen, Horvath, Steve, Evseenko, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924946/ https://www.ncbi.nlm.nih.gov/pubmed/36638270 http://dx.doi.org/10.1111/acel.13773 |
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