Genetic basis of enhanced stress resistance in long‐lived mutants highlights key role of innate immunity in determining longevity

Mutations that extend lifespan are associated with enhanced resistance to stress. To better understand the molecular mechanisms underlying this relationship, we directly compared lifespan extension, resistance to external stressors, and gene expression in a panel of nine long‐lived Caenorhabditis el...

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Detalles Bibliográficos
Autores principales: Soo, Sonja K., Traa, Annika, Rudich, Zenith D., Moldakozhayev, Alibek, Mistry, Meeta, Van Raamsdonk, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924947/
https://www.ncbi.nlm.nih.gov/pubmed/36514863
http://dx.doi.org/10.1111/acel.13740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924947/
https://www.ncbi.nlm.nih.gov/pubmed/36514863
http://dx.doi.org/10.1111/acel.13740

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