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Genetic basis of enhanced stress resistance in long‐lived mutants highlights key role of innate immunity in determining longevity
Mutations that extend lifespan are associated with enhanced resistance to stress. To better understand the molecular mechanisms underlying this relationship, we directly compared lifespan extension, resistance to external stressors, and gene expression in a panel of nine long‐lived Caenorhabditis el...
Autores principales: | Soo, Sonja K., Traa, Annika, Rudich, Zenith D., Moldakozhayev, Alibek, Mistry, Meeta, Van Raamsdonk, Jeremy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924947/ https://www.ncbi.nlm.nih.gov/pubmed/36514863 http://dx.doi.org/10.1111/acel.13740 |
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