Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation

Blood–brain barrier dysfunction (BBBD) and accumulation of senescent astrocytes occur during brain aging and contribute to neuroinflammation and disease. Here, we explored the relationship between these two age‐related events, hypothesizing that chronic hippocampal exposure to the blood‐borne protei...

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Detalles Bibliográficos
Autores principales: Preininger, Marcela K., Zaytseva, Dasha, Lin, Jessica May, Kaufer, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924950/
https://www.ncbi.nlm.nih.gov/pubmed/36606305
http://dx.doi.org/10.1111/acel.13747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924950/
https://www.ncbi.nlm.nih.gov/pubmed/36606305
http://dx.doi.org/10.1111/acel.13747

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