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Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation
Blood–brain barrier dysfunction (BBBD) and accumulation of senescent astrocytes occur during brain aging and contribute to neuroinflammation and disease. Here, we explored the relationship between these two age‐related events, hypothesizing that chronic hippocampal exposure to the blood‐borne protei...
Autores principales: | Preininger, Marcela K., Zaytseva, Dasha, Lin, Jessica May, Kaufer, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924950/ https://www.ncbi.nlm.nih.gov/pubmed/36606305 http://dx.doi.org/10.1111/acel.13747 |
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